If you are looking for a simple online tool that allows you to collaborate with clients and others working on your projects then have a look at Basecamp.
It seems to be well geared to being a fairly quick and easy way to setup project extranets and something that should go some way to reducing the amount of emails and files flying around on your projects.
Here is a recent article on it worth reading:
http://www.cmswire.com/cms/featured-articles/basecamp-project-collaboration-utopia-000902.php
You will find links to other project collaboration tools tagged as “software” in our del.icio.us link collection
Posted by Jason Coghlan 
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